| T8328 |
STING agonist-1
|
702662-50-8
|
98%
|
|
|
STING agonist-1 (G10) is a human-specific STING agonist,elicits antiviral activity against emerging Alphaviruses.
|
| T9853 |
STING activator Compound 53
|
2259624-71-8
|
98%
|
|
|
STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised ...
|
| T10252L2 |
ADU-S100 ammonium salt
|
1638750-96-5
|
98%
|
|
|
ADU-S100 ammonium salt (ML RR-S2 CDA ammonium salt) is an activator of stimulator of interferon genes (STING). ADU-S100 ammonium salt leads to potent and systemi...
|
| T13015 |
STING agonist-4
|
2138300-40-8
|
|
|
|
STING agonist-4 is an agonist of stimulator of Interferon Genes (STING) receptor(IC50 of 20 nM).
|
| T13613 |
ChX710
|
2438721-44-7
|
|
|
|
ChX710 activates the type I interferon response to cytosolic DNA by priming specific Interferon-Stimulated Genes (ISGs), inducing the ISRE promoter sequence, and...
|
| T9554 |
SN-008
|
2249106-01-0
|
96.83%
|
|
|
SN-008 is a less active analog SN-011 which is a STING antagonist. SN-008 can be used as a negative control.
|
| T7329 |
C-178
|
329198-87-0
|
98%
|
|
|
C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation and prevents recruitment and phosphorylation of TBK1 in HEK293T cells...
|
| T9137 |
SN-011
|
2249435-90-1
|
98.1%
|
|
|
SN-011 (GUN35901) is a STING inhibitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING- mediated disease. It is a dem...
|
| T9029 |
STING-IN-3
|
2244881-69-2
|
98.15%
|
|
|
STING-IN-3 (C-171) is an inhibitor of stimulator of interferon genes (STING). It binds to STING, inhibits its palmitoylation, and prevents the recruitment and ph...
|
| T8798 |
MSA-2
|
129425-81-6
|
98.19%
|
|
|
MSA-2 is a potent and orally available non-nucleotide STING agonist.
|
| T6273 |
Vadimezan
|
117570-53-3
|
98.5%
|
|
|
Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and in...
|
| T7081 |
CCCP
|
555-60-2
|
98.55%
|
|
|
CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the ...
|
| T72482 |
Dazostinag disodium
|
2553413-93-5
|
98.59%
|
|
|
Dazostinag disodium (TAK-676) is a novel stimulator of interferon genes (STING) agonist and immune system modulator with antitumor activity that activates dendri...
|
| T8655 |
SR-717
|
2375421-09-1
|
98.64%
|
|
|
SR-717 is a cGAMP analog, a non-nucleoside STING agonist that induces a "closed" activation conformation of STING. SR-717 has antitumor activity and promotes act...
|
| T6919 |
Omaveloxolone
|
1474034-05-3
|
98.7%
|
|
|
Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
|
| T9028 |
STING-IN-2
|
346691-38-1
|
98.76%
|
|
|
STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. C-170 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). It can be used f...
|
| T74809 |
STING agonist-30
|
2951078-67-2
|
99.04%
|
|
|
STING agonist-30 is a potent STING agonist that triggers STING-dependent immune activation.STING agonist-30 shows broad-spectrum inhibitory effects against a var...
|
| T5516 |
DiABZI STING agonist-1 trihydrochloride
|
2138299-34-8
|
99.18%
|
|
|
diABZI STING agonist-1 (trihydrochloride) is stimulator of interferon genes (STING) receptor agonist.
|
| T5154 |
C-176
|
314054-00-7
|
99.40%
|
|
|
C-176 (STING inhibitor 1) is a strong, covalent mouse STING inhibitor
|
| T9204 |
SN-001
|
727699-84-5
|
99.51%
|
|
|
SN-001 was reported as a STING inhbiitor, which inhibited the activation of the STING signal pathway and to prevent or treat a STING- mediated disease.
|
