T1740 |
BD-1047 dihydrobromide
|
138356-21-5
|
98%
|
|
BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in animal models predictive of efficacy i...
|
T22904 |
L-745870 trihydrochloride
|
866021-03-6
|
98%
|
|
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.
|
T1885 |
Siramesine hydrochloride
|
224177-60-0
|
98%
|
|
Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit ...
|
T77593 |
KSK67
|
2566715-93-1
|
98%
|
|
KSK67 is a selective dual antagonist of sigma-2 and histamine H3 receptors with inhibitory effects on H3 receptors, sigma-1, and sigma-2 receptors, with Ki value...
|
T13510 |
Sigma-LIGAND-1
|
139652-01-0
|
100%
|
|
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000...
|
T12912 |
Sigma-1 receptor antagonist 3
|
1639220-17-9
|
100%
|
|
Sigma-1 receptor antagonist 3 is a potent and selective antagonist of Sigma-1 (σ1) receptor(Ki : 1.14 nM), has the potential for the neuropathic pain.
|
T1180 |
Blonanserin
|
132810-10-7
|
100%
|
|
Blonanserin (AD-5423) is an atypical antipsychotic approved in Japan in January, 2008. Relative to many other antipsychotics, blonanserin has an improved tolerab...
|
T15034 |
Roluperidone
|
359625-79-9
|
96.46%
|
|
Roluperidone (CYR-101) is a novel cyclic amide derivative. It has high equipotent affinities for 5-HT2A and σ2 receptors (Ki of 7.53 nM and 8.19 nM for 5-HT2A an...
|
T21788 |
BD 1008 dihydrobromide
|
138356-09-9
|
97.81%
|
|
BD 1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (Ki = 2 nM). BD 1008 dihydrobromide have high affinity for sigma1 receptors, modera...
|
T7488 |
BD1063 dhydrochloride
|
206996-13-6
|
98%
|
|
BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
|
T5969 |
Ditolylguanidine
|
97-39-2
|
98%
|
|
Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).
|
T22612 |
BMY-14802 hydrochloride
|
105565-55-7
|
98.64%
|
|
BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects. BMY-14802 hydrochloride is...
|
T3597 |
Cutamesine dihydrochloride
|
165377-44-6
|
98.83%
|
|
Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows selectivity for σ1 over σ2 receptors, and inhibi...
|
T20797 |
NE-100 hydrochloride
|
149409-57-4
|
98.85%
|
|
NE-100 hydrochloride (NE-100 HCl) is a potent and selective antagonist of σ1 (IC50 = 4.16 nM) with antipsychotic activity. NE100 HCl also suppresses ER stress-in...
|
T67739 |
BMY-14802
|
105565-56-8
|
98.93%
|
|
BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.
|
T15393 |
Glycerol phenylbutyrate
|
611168-24-2
|
99.00%
|
|
Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is a sigma-2 (σ2) receptor ligand (pKi: 8.02).
|
T72059 |
S1R agonist 2
|
150085-21-5
|
99.04%
|
|
S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
|
T39211 |
PD 144418 oxalate
|
1794760-28-3
|
99.08%
|
|
PD 144418 oxalate is a highly potent and selective sigma 1 (σ1) receptor ligand, displaying a Ki value of 0.08 nM for σ1 and 1377 nM for σ2. It exhibits negligib...
|
T4596 |
4-IBP
|
155798-08-6
|
99.12%
|
|
4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .
|
T8834 |
EST64454 hydrochloride
|
1950569-11-5
|
99.15%
|
|
EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the potential for Pain Management.
|