| T27205 |
DPI 201-106
|
97730-95-5
|
98%
|
|
|
DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delay...
|
| T6566 |
Levobupivacaine hydrochloride
|
27262-48-2
|
98%
|
|
|
Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bup...
|
| T37688 |
Cyfluthrin
|
68359-37-5
|
98%
|
|
|
Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests....
|
| T6086 |
Clopamide
|
636-54-4
|
98%
|
|
|
Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.
|
| T0275 |
Meticrane
|
1084-65-7
|
98%
|
|
|
Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.
|
| T7547 |
Ralfinamide mesylate
|
202825-45-4
|
98%
|
|
|
Ralfinamide mesylate (FCE-26742A (mesylate)) is an orally available Na+ channel blocker.
|
| TN1254 |
3'-Methoxydaidzein
|
21913-98-4
|
98%
|
|
|
3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 ...
|
| T7502 |
PF 05089771 tosylate
|
1430806-04-4
|
98%
|
|
|
PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respec...
|
| T2131 |
Articaine hydrochloride
|
23964-57-0
|
98%
|
|
|
Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.
|
| TQ0157 |
EIPA
|
1154-25-2
|
98%
|
|
|
EIPA (L593754) (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
|
| T31716 |
Etidocaine Hydrochloride
|
36637-19-1
|
|
|
|
Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.
|
| T9685 |
DS-1971a
|
1450595-86-4
|
|
|
|
DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.
|
| T6782L |
Benzocaine xHCl(94-09-7(free base))
|
T6782L
|
|
|
|
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).
|
| T1332 |
Permethrin
|
52645-53-1
|
|
|
|
Permethrin (NRDC-143) is a pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.
|
| T0030 |
Bupivacaine hydrochloride
|
18010-40-7
|
|
|
|
Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels i...
|
| T0511 |
Tolperisone hydrochloride
|
3644-61-9
|
|
|
|
Tolperisone hydrochloride (Muscalm), a centrally acting muscle relaxant, is used in the therapy of pathologically increased tone of the cross-striated muscle res...
|
| T21769L |
β-Pompilidotoxin Acetate
|
T21769L
|
|
|
|
β-Pompilidotoxin Acetate is a wasp venom peptide. β-Pompilidotoxin Acetate can slow sodium channel inactivation and increase steady-state sodium current in cells...
|
| T6955 |
Propafenone hydrochloride
|
34183-22-7
|
|
|
|
Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventric...
|
| T0029 |
Procaine
|
59-46-1
|
|
|
|
Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia...
|
| T9234 |
Tocainide hydrochloride
|
35891-93-1
|
|
|
|
Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker. It blocks the sodium channels in the pain-producin...
|
