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Stemness kinase

Stemness kinase refers to cancer stemness-associated kinases, including multiple serine-threonine stemness kinases, such as Nanog. Cancer stemness, referring to the stem-cell-like phenotype of cancer cells. Cancer stem cells (CSCs) are cells that, like normal stem cells, have the ability to self-renew by dividing as well as to give rise to all cell types within a tumor; consequently, they are also referred to as tumor-initiating cells (TICs). The strong emphasis on tumor initiation makes the in vivo tumorigenicity assay a gold standard for defining cancer stemness.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T3995 Amcasertib 1129403-56-0 98%
Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.
Amcasertib
T3995
Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.