T3674 |
Hydroxysafflor yellow A
|
78281-02-4
|
97.1%
|
|
Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver fro...
|
T6856 |
Halofuginone
|
55837-20-2
|
97.67%
|
|
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml ...
|
T1800 |
GW788388
|
452342-67-5
|
98%
|
|
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.
|
T2109 |
SD-208
|
627536-09-8
|
98%
|
|
SD-208 (ALK5 Inhibitor V), a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.
|
T9523 |
TGFβRI-IN-3
|
2763602-67-9
|
98.02%
|
|
TGFβRI-IN-3 inhibits TGFβR1 with an IC 50 of 0.79 nM with 2000-fold selectivity against MAP4K4. TGFβRI-IN-3 is a highly selective TGFβR1 inhibitor that has poten...
|
T3025 |
Asiaticoside
|
16830-15-2
|
98.07%
|
|
Asiaticoside (Emdecassol) (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wo...
|
T8730 |
BMS986260
|
2001559-19-7
|
98.22%
|
|
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).
|
T1943 |
ML347
|
1062368-49-3
|
98.3%
|
|
ML347 (LDN 193719)(DN193719) is a highly specific ALK1/2 inhibitor ( IC50: 46/32 nM), and the selectivity for ALK2 is >300-fold than ALK3.
|
TQ0184 |
Chebulinic acid
|
18942-26-2
|
98.4%
|
|
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
|
T3524 |
Halofuginone hydrobromide
|
64924-67-0
|
98.5%
|
|
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of...
|
T2565 |
Hesperetin
|
520-33-2
|
98.54%
|
|
Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges....
|
T2462 |
SB-505124
|
694433-59-5
|
98.74%
|
|
SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5.
|
T38752 |
EW-7195
|
1352609-28-9
|
98.76%
|
|
EW-7195 is a selective and potent inhibitor of ALK5 (TGFβR1) with an IC50 value of 4.83 nM.EW-7195 has an affinity for ALK5 that is more than 300-fold higher tha...
|
T3031 |
A 83-01
|
909910-43-6
|
98.76%
|
|
A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse f...
|
T6337 |
RepSox
|
446859-33-2
|
98.8%
|
|
RepSox (ALK5 Inhibitor II) is a potent and selective of the TGFβR-1/ALK5 inhibitor.
|
T6146 |
Dorsomorphin dihydrochloride
|
1219168-18-9
|
98.89%
|
|
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on s...
|
T8785 |
HALOFUGINONE LACTATE
|
82186-71-8
|
99.02%
|
|
HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. febrifuga.Halofuginone ...
|
T4662 |
SJ000291942
|
425613-09-8
|
99.07%
|
|
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.
|
T1935 |
LDN193189
|
1062368-24-4
|
99.11%
|
|
LDN193189 (LDN-193189) (DM 3189) is a selective BMP signaling inhibitor, inhibiting the transcriptional activity of ALK2 and ALK3 (IC50s: 0.8/0.8/5.3/16.7 nM for...
|
T4283 |
SRI-011381
|
1629138-41-5
|
99.11%
|
|
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
|