TOPK

T-LAK cell-originated protein kinase (TOPK) is a MAPKK-like kinase which plays a role in cell cycle regulation and mitotic progression. As a consequence, TOPK expression is minimal in differentiated cells, although its overexpression is a pathophysiological feature of many tumours. Hence, TOPK has garnered interest as a cancer-specific biomarker and biochemical target with the potential to enhance cancer therapy whilst causing minimal harm to normal tissues.

Cat. No.	製品名	CAS No.	Purity
T4135	OTS964 hydrochloride	1338545-07-5	98.02%
T4135	OTS964 hydrochloride (OTS964) is a potent and selective TOPK inhibitor with potential anticancer activity.
T15481	HI-TOPK-032	487020-03-1	98.69%
T15481	HI-TOPK-032 is an effective and specific inhibitor of TOPK.
T4134	OTS514 hydrochloride	2319647-76-0	98.93%
T4134	OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).
T1756	Ilaprazole sodium	172152-50-0	99.06%
T1756	Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumul...
T1756L	Ilaprazole	172152-36-2	99.08%
T1756L	Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also ...
T0199	Cephradine	38821-53-3	mixture
T0199	Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.
T4134L	OTS514	1338540-63-8
T4134L	OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed th...