| T28548 |
RN9893
|
1803003-68-0
|
98%
|
|
|
RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.
|
| T7572 |
RN-1734
|
946387-07-1
|
98%
|
|
|
RN-1734 is selective TRPV4 channel antagonist(IC50 of 2.3 μM,5.9 μM,3.2 μM for hTRPV4, mTRPV4 and rTRPV4,respectively)
|
| T12849 |
SAR7334
|
1333210-07-3
|
98%
|
|
|
SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).
|
| T6977 |
SB-366791
|
472981-92-3
|
98%
|
|
|
SB-366791 is a new and selective cinnamide TRPV1 antagonist.
|
| T2007 |
RQ-00203078
|
1254205-52-1
|
98%
|
|
|
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist.
|
| T8562 |
A 425619
|
581809-67-8
|
98%
|
|
|
A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist
|
| T4680 |
HC-067047
|
883031-03-6
|
98%
|
|
|
HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .
|
| TQ0157 |
EIPA
|
1154-25-2
|
98%
|
|
|
EIPA (L593754) (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
|
| T40042 |
Evifacotrep
|
2413739-88-3
|
98%
|
|
|
Evifacotrep is a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100). Evifacotrep can be used for the research of neur...
|
| T10300 |
AMG2850
|
1470018-52-0
|
98%
|
|
|
AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).
|
| T37428 |
TRPC6-PAM-C20
|
667427-75-0
|
98%
|
|
|
TRPC6-PAM-C20 is a selective TRPC6 positive allosteric modulator. TRPC6-PAM-C20 induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 wi...
|
| T9818 |
NGD-8243
|
573678-04-3
|
98%
|
|
|
NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for prevention and...
|
| T21543 |
AP 18
|
55224-94-7
|
98%
|
|
|
AP-18 is a potent and selective TRPA1 inhibitor. AP-18 inhibits activation of TRPA1 induced by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human a...
|
| T16763 |
RN-1747
|
1024448-59-6
|
|
|
|
RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: 0.77 μM, 4.0 μM, and 4.1 μM for hTRPV4, mTRPV4, and rTRPV...
|
| T7205 |
A-967079
|
1170613-55-4
|
|
|
|
A 967079 is a potent, selective, and bioavailable inhibitor of the TRPA1 channel, with IC50 values of 67 and 289 nM for the human and rat isoforms, respectively....
|
| TN6791 |
Palvanil
|
69693-13-6
|
|
|
|
Palvanil (Hexadecanamide) is a fast desensitizing agonist of TRPV1. it may be promising agents in the therapy of IBS since it modulates intestinal motility and r...
|
| T8425 |
Linoleoyl Ethanolamide
|
68171-52-8
|
|
|
|
Linoleoyl Ethanolamide is an endocannabinoid agent. It acts by binding to TRPV1 increasing ERK phosphorylation and AP-1 dependent transcription in CB-receptor in...
|
| T15543 |
IA-Alkyne
|
930800-38-7
|
|
|
|
IA-Alkyne (Iodoacetamide-alkyne) is a TRP channel (TRPC) agonist. IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactiv...
|
| T24477 |
MK6-83
|
1062271-24-2
|
|
|
|
MK6-83 is the transient receptor potential channel ML3 agonist.
|
| T34081 |
Piromelatine
|
946846-83-9
|
100%
|
|
|
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibito...
|
