| T2368L |
Edoxaban
|
480449-70-5
|
98%
|
|
|
Edoxaban (Lixiana) (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with K i s of 0.561 nM and 2.98 nM for free FXa and prothrombinase...
|
| T41031 |
Protamine sulfate
|
9009-65-8
|
98%
|
|
|
Protamine sulfate is a polycationic peptide that serves as an antiheparin agent. This compound can neutralize the anticoagulant action of heparin and enhance lip...
|
| T0389 |
Dabigatran etexilate
|
211915-06-9
|
98%
|
|
|
Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.
|
| T2562 |
Eltrombopag
|
496775-61-2
|
98%
|
|
|
Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet thr...
|
| T6370 |
AEBSF hydrochloride
|
30827-99-7
|
98%
|
|
|
AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.
|
| T25364L |
Efegatran sulfate
|
126721-07-1
|
98%
|
|
|
Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.
|
| T22323 |
Enoxaparin sodium
|
679809-58-6
|
|
|
|
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment my...
|
| T6236 |
Ozagrel
|
82571-53-7
|
100%
|
|
|
Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative...
|
| T22246 |
Argatroban Monohydrate
|
141396-28-3
|
100%
|
|
|
Argatroban Monohydrate is a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.
|
| T0448 |
(S)-(+)-Ibuprofen
|
51146-56-6
|
100%
|
|
|
(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).
|
| T5519 |
Bivalirudin
|
128270-60-0
|
100.00%
|
|
|
Bivalirudin (BG-8967) is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clotting activi...
|
| T0449 |
Menadione
|
58-27-5
|
97.64%
|
|
|
Menadione (Vitamin K3) is a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaqu...
|
| T68086 |
Imitrodast
|
114686-12-3
|
98.04%
|
|
|
Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, and cardiov...
|
| T17265 |
Ximelagatran
|
192939-46-1
|
98.09%
|
|
|
Ximelagatran (H 376-95), a direct thrombin inhibitor, can be taken orally and acts solely by inhibiting the actions of thrombin. Ximelagatran is converted to the...
|
| T68002 |
Naroparcil
|
120819-70-7
|
98.11%
|
|
|
Naroparcil, an orally available thioglycoside analog of 4-methylumbelliferyl β-D-xyloside, showed antithrombotic effects in the Wessler sludge model of venous th...
|
| T6295 |
Dabigatran
|
211914-51-1
|
98.65%
|
|
|
Dabigatran (BIBR 953ZW) is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to ...
|
| T10951 |
Dabigatran ethyl ester hydrochloride
|
211914-50-0
|
98.7%
|
|
|
Dabigatran ethyl ester hydrochloride is an effective inhibitor of ribosyl dihydronicotinic acid amide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and is a ...
|
| T11994 |
Melagatran
|
159776-70-2
|
98.86%
|
|
|
Melagatran, a direct and orally active thrombin inhibitor, specifically inhibits thrombin without affecting other enzymes in the coagulation cascade or fibrinoly...
|
| T12771 |
RS-601
|
207987-59-5
|
99.31%
|
|
|
RS-601 is a potent dual leukotriene D4/thromboxane A2 inhibitor that inhibits antigen-induced airway hyperresponsiveness (AHR) and shows asthmatic effects in a g...
|
| T67959 |
Pirodomast
|
108310-20-9
|
99.34%
|
|
|
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is wea...
|
