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Thyroid hormone receptor(THR)

The thyroid hormone receptor (TR) is a type of nuclear receptor that is activated by binding thyroid hormone.TRs act as transcription factors, ultimately affecting the regulation of gene transcription and translation. These receptors also have non-genomic effects that lead to second messenger activation, and corresponding cellular response.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T40548 NH-3 447415-26-1 98%
NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the ...
T16018 MB-07811 852948-13-1 98%
MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity. MB-07811 is an agonist of liver-targete...
T13435 TR antagonist 1 500794-88-7 98%
TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TRα and TRβ, respectively) that can be used to study diseas...
T21535 Parathyroid Hormone (1-34), bovine 12583-68-5 98%
Parathyroid Hormone (1-34), bovine is a parathyroid hormone (PTH) receptor agonist that is part of the parathyroid hormone family. Parathyroid Hormone (1-34), bo...
T0840 Methimazole 60-56-0 98%
Methimazole (Thiamazole) is an antithyroid compound with significant hepatotoxicity and is often used in the study of hyperthyroidism.
T6956 Protirelin 24305-27-9 98%
Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin.
TP1906L1 DPC AJ1951 acetate TP1906L1 98%
DPC-AJ1951 acetate, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized ...
T6956L Protirelin Acetate(24305-27-9 free base) T6956L 100%
Protirelin Acetate(24305-27-9 free base) (Thyroliberin Acetate) is a tripeptide that stimulates the release of thyrotropin and prolactin.
TP1022 Protirelin Acetate 120876-23-5 96.17%
Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.
T10855 CO23 1370363-74-8 96.52%
CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.
T9691L (D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate 96.84%
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membr...
T7578 REVERSE T3 5817-39-0 97.66%
Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.
T1669 Liothyronine sodium 55-06-1 98%
Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyron...
T16442 PCO371 1613373-33-3 98%
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimeth...
T5360 Eprotirome 355129-15-6 98.25%
Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.
T11101 DS08210767 2376334-75-5 98.33%
DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.
T23673 AH-3960 862907-48-0 98.44%
AH-3960 is an thyroid hormone receptor-1 (PTHR1) agonist.
T0864 L-Thyroxine 51-48-9 98.64%
L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYRO...
T5313 Sobetirome 211110-63-3 98.72%
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
T3595 Resmetirom 920509-32-6 99.05%
Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist.
NH-3
T40548
NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the ...
MB-07811
T16018
MB-07811 (VK-2809) is an orally active HepDirect prodrug of MB07344 with cholesterol and triglycerides lowering activity. MB-07811 is an agonist of liver-targete...
TR antagonist 1
T13435
TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TRα and TRβ, respectively) that can be used to study diseas...
Parathyroid Hormone (1-34), bovine
T21535
Parathyroid Hormone (1-34), bovine is a parathyroid hormone (PTH) receptor agonist that is part of the parathyroid hormone family. Parathyroid Hormone (1-34), bo...
Methimazole
T0840
Methimazole (Thiamazole) is an antithyroid compound with significant hepatotoxicity and is often used in the study of hyperthyroidism.
Protirelin
T6956
Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin.
DPC AJ1951 acetate
TP1906L1
DPC-AJ1951 acetate, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized ...
Protirelin Acetate(24305-27-9 free base)
T6956L
Protirelin Acetate(24305-27-9 free base) (Thyroliberin Acetate) is a tripeptide that stimulates the release of thyrotropin and prolactin.
Protirelin Acetate
TP1022
Protirelin Acetate (TRH Acetate) is a thyrotropin-releasing hormone, stimulating the release of thyrotropin and prolactin from the anterior pituitary.
CO23
T10855
CO23 is a blood-brain barrier penetrant and selective TRα agonist and can be used in studies about the regulation of growth and development.
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate
T9691L
(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate is a highly potent antagonist of parathyroid hormone (PTH) The Ki value is 69 nM in bovine renal cortical membr...
REVERSE T3
T7578
Reverse T3 (3,3',5'-triiodo-L-thyronine) inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.
Liothyronine sodium
T1669
Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyron...
PCO371
T16442
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimeth...
Eprotirome
T5360
Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.
DS08210767
T11101
DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.
AH-3960
T23673
AH-3960 is an thyroid hormone receptor-1 (PTHR1) agonist.
L-Thyroxine
T0864
L-Thyroxine (NSC 36397) is the major hormone derived from the thyroid gland. L-Thyroxine (NSC 36397) is synthesized via the iodination of tyrosines (MONOIODOTYRO...
Sobetirome
T5313
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
Resmetirom
T3595
Resmetirom (VIA-3196) is a highly selective thyroid hormone receptor β (THR-β) agonist.
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