| T6467 |
Cardioxane
|
149003-01-0
|
98%
|
|
|
Cardioxane (ADR-529) is a cardio-protective drug.
|
| TQ0134 |
Podocarpusflavone A
|
22136-74-9
|
98%
|
|
|
Podocarpusflavone A is a DNA topoisomerase I inhibitor. It has moderated anti-proliferative activity induce cell apoptosis in MCF-7.
|
| T1123 |
Camptothecin
|
7689-03-4
|
98%
|
|
|
Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity. Cam...
|
| T5820 |
Amsacrine hydrochloride
|
54301-15-4
|
98%
|
|
|
Amsacrine hydrochloride (acridinyl anisidide hydrochloride) is topoisomerase II inhibitor , is used in the treatment of acute myelogenous leukemia.
|
| T1444 |
Lomefloxacin
|
98079-51-7
|
98%
|
|
|
Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.
|
| T2830 |
Betulinic acid
|
472-15-1
|
|
|
|
Betulinic acid (ALS-357) is a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) which has ...
|
| T15507 |
Hycanthone
|
3105-97-3
|
|
|
|
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II...
|
| T1451 |
Levofloxacin hydrate
|
138199-71-0
|
|
|
|
Levofloxacin hydrate (Cravit hydrate) is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacter...
|
| T8747 |
Levofloxacin hydrochloride
|
177325-13-2
|
|
|
|
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxac...
|
| T3181 |
SW044248
|
522650-83-5
|
|
|
|
SW044248 is a noncanonical Top1 inhibitor. It has selective toxicity for NSCLC cells.
|
| T3S1957 |
9-amino-CPT
|
91421-43-1
|
|
|
|
9-amino-CPT (Aminocamptothecin) is an inhibitor of topoisomerase I with potent anticancer activity.
|
| T6588 |
Mitoxantrone
|
65271-80-9
|
|
|
|
Mitoxantrone (mitozantrone) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting ...
|
| T7309 |
TAS-103 dihydrochloride
|
174634-09-4
|
|
|
|
TAS-103 dihydrochloride (BMS-247615 dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.
|
| T1620 |
Pazufloxacin Mesylate
|
163680-77-1
|
|
|
|
Pazufloxacin Mesylate (T-3762) is a fluoroquinolone antibiotic.
|
| T0331 |
Moxifloxacin hydrochloride
|
186826-86-8
|
100%
|
|
|
Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria as well as atypical path...
|
| T36968 |
ARN-21934
|
2230854-93-8
|
100%
|
|
|
ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. ARN-21934 inhibits DNA relaxation wit...
|
| T11090L1 |
Aldoxorubicin hydrochloride
|
1361563-03-2
|
100%
|
|
|
Aldoxorubicin hydrochloride is an albumin-binding prodrug of Doxorubicin, a DNA topoisomerase II inhibitor. Aldoxorubicin hydrochloride is released from albumin ...
|
| T0425 |
Pefloxacin Mesylate
|
70458-95-6
|
100%
|
|
|
Pefloxacin Mesylate (Pefloxacinium mesylate) is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positiv...
|
| T8333 |
Aurintricarboxylic acid
|
4431-00-9
|
95%
|
|
|
Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by ...
|
| T3339 |
Sophoridine
|
6882-68-4
|
96.35%
|
|
|
Sophoridine (Dihydro-5-episophocarpine), a natural anticancer drug, has been used in China for decades. A series of novel N-substituted Sophoridinic acid derivat...
|
