| T15109 |
DGAT1-IN-1
|
1449779-49-0
|
98%
|
|
|
DGAT1-IN-1 is a potent inhibitor of diacylglycerol O- acyltransferase type 1(DGAT1, IC50 of < 10 nM).
|
| T6844 |
GGTI298 Trifluoroacetate
|
1217457-86-7
|
98%
|
|
|
GGTI298 Trifluoroacetate (GGTI 298 TFA salt) is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycl...
|
| T4681 |
T863
|
701232-20-4
|
98%
|
|
|
T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA bi...
|
| T11282 |
FGTI-2734
|
1247018-19-4
|
98%
|
|
|
FGTI-2734 is a dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor, exhibiting IC50 values of 250 nM and 520 nM for FT and GGT-1, r...
|
| T38050 |
CP-609754
|
1190094-64-4
|
|
|
|
CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombin...
|
| T25210 |
CBHcy
|
88096-02-0
|
100%
|
|
|
CBHcy is a dual-substrate analogue, a specific BHMT inhibitor that causes betaine-homocysteine S-methyltransferase (BHMT) to adopt the same conformation as the t...
|
| T0525 |
Flopropione
|
2295-58-1
|
100%
|
|
|
Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.
|
| T10512 |
Prenyl-IN-1
|
360561-53-1
|
100%
|
|
|
Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects i...
|
| T16398 |
Opicapone
|
923287-50-7
|
100%
|
|
|
Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for ...
|
| T35626 |
AMP-Deoxynojirimycin
|
216758-20-2
|
100%
|
|
|
AMP-Deoxynojirimycin (AMP-DNM) is a potent inhibitor of ceramide glucosyltransferase and GCase 2.AMP-Deoxynojirimycin is a potent inhibitor of GlcCer biosynthesi...
|
| T1455 |
Nialamide
|
51-12-7
|
93.91%
|
|
|
Nialamide (Nialamid) is an MAO inhibitor that is used as an antidepressive agent.
|
| T6365 |
A 922500
|
959122-11-3
|
97.66%
|
|
|
A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and 24 nM, respectively, good selectivity over related acyltransferas...
|
| T4473 |
Ibiglustat
|
1401090-53-6
|
97.97%
|
|
|
Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation o...
|
| T8489 |
Minodronic acid monohydrate
|
155648-60-5
|
98%
|
|
|
Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption inhibitor.
|
| T6302 |
Lonafarnib
|
193275-84-2
|
98%
|
|
|
Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
|
| T7439 |
3-Methoxybenzamide
|
5813-86-5
|
98%
|
|
|
3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.
|
| T1599L |
Ibandronate sodium
|
138844-81-2
|
98.13%
|
|
|
Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
|
| T2700 |
FTI-277 hydrochloride
|
180977-34-8
|
98.19%
|
|
|
FTI-277 hydrochloride (FTI 277 HCl) is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than th...
|
| T2765 |
Rosmarinic acid
|
20283-92-5
|
98.19%
|
|
|
Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities. It inhibits MAO-A, MAO-B, and C...
|
| T27691 |
JNJ-DGAT2-A
|
1962931-71-0
|
98.2%
|
|
|
JNJ-DGAT2-A, a specific inhibitor of DGAT2(IC50 = 0.14 μM), can be used in studies about the synthesis of triglycerides.
|
