T3686 |
10074-G5
|
413611-93-5
|
98%
|
|
10074-G5 is an inhibitor of c-Myc-Max dimerization.
|
T12133 |
MYCi975
|
2289691-01-4
|
98%
|
|
MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.
|
TN6508 |
Trachelogenin
|
34209-69-3
|
98%
|
|
Trachelogenin ((-)-Trachelogenin), an HCV entry inhibitor, has antiproliferative effects, and its mechanism is related to affecting the phosphorylation of key pr...
|
T9628 |
10074-A4
|
312631-87-1
|
98%
|
|
10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from th...
|
T15665 |
KJ Pyr 9
|
581073-80-5
|
|
|
KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).
|
T12134 |
MYCMI-6
|
681282-09-7
|
97.77%
|
|
MYCMI-6 (NSC-354961) is a potent and selective inhibitor of endogenous MYC:MAX protein interactions,reduces proliferation and induces massive apoptosis in tumor ...
|
T9033 |
BTYNB
|
304456-62-0
|
98%
|
|
BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and r...
|
T9061 |
EN4
|
1197824-15-9
|
98.19%
|
|
EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits ...
|
TN1892 |
Lusianthridin
|
87530-30-1
|
99.11%
|
|
Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-...
|
T12132 |
MYCi361
|
2289690-31-7
|
99.13%
|
|
MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).
|
T10352 |
APTO-253
|
916151-99-0
|
99.43%
|
|
APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 ...
|
T4252 |
ML327
|
1883510-31-3
|
99.48%
|
|
ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).
|
T4367 |
Mycro 3
|
944547-46-0
|
99.51%
|
|
Mycro 3 is potent and selective for c-Myc in whole cell assays.
|
T9093 |
NY2267
|
886053-73-2
|
99.6%
|
|
NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester...
|
T3048 |
10058-F4
|
403811-55-2
|
99.82%
|
|
10058-F4 (c-Myc Inhibitor) is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target g...
|
T0617 |
Nicotinamide N-oxide
|
1986-81-8
|
99.9%
|
|
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD...
|
T60019 |
VPC-70063
|
13571-44-3
|
99.93%
|
|
VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inh...
|
TN4581 |
Moracin D
|
69120-07-6
|
98%
|
|
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
|
T10702 |
CBP/p300-IN-2
|
2158265-96-2
|
98%
|
|
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc) extracted from patent WO2017205538A1 (example 25).
|
TN1354 |
Aaptamine
|
85547-22-4
|
98%
|
|
Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
|