iGluR

Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate.[1] They mediate the majority of excitatory synaptic transmission throughout the central nervous system and are key players in synaptic plasticity, which is important for learning and memory. iGluRs have been divided into four subtypes on the basis of their ligand binding properties (pharmacology) and sequence similarity: AMPA receptors, kainate receptors, NMDA receptors and delta receptors.

Cat. No.	製品名	CAS No.	Purity
T3407	Rapastinel	117928-94-6	98%
T3407	Rapastinel (TPPT-amide) (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator.
T12406	PEPA	141286-78-4	98%
T12406	PEPA is an allosteric AMPA receptors modulator; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity.
T22542	1-Aminocyclobutanecarboxylic acid	22264-50-2	98%
T22542	1-Aminocyclobutanecarboxylic acid (ACBC) is a NMDA receptor partial agonist. 1-Aminocyclobutanecarboxylic acid act at the glycine site, NR1[1].
T3957	Farampator	211735-76-1	98%
T3957	Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.
T6871	L-Glutamic acid monosodium salt	142-47-2	98%
T6871	L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.
T20571	Cis-PDA	46026-75-9	98%
T20571	cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.
T10930	D-AP5	79055-68-8	98%
T10930	D-AP5 (D-APV) is a NMDA receptor antagonist.
T12187L	Naspm trihydrochloride	1049731-36-3	98%
T12187L	Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride) is a synthetic analogue of Joro spider toxin and is an antagonist of calcium permeable AMPA (...
T9133	Caroverine hydrochloride	55750-05-5	98%
T9133	Caroverine hydrochloride (Caroverine HCL) is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and c...
T1443	Memantine hydrochloride	41100-52-1	98%
T1443	Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects. Memantine hydrochloride has been proposed as an antiparki...
T0015	Mephenesin	59-47-2	98%
T0015	Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.
T1946	Felbamate	25451-15-4	98%
T1946	Felbamate (W-554) is an Anti-epileptic Agent. The physiologic effect of felbamate is by means of Decreased Central Nervous System Disorganized Electrical Activit...
T16451	PEAQX tetrasodium hydrate	T16451	98%
T16451	PEAQX tetrasodium hydrate (PEAQX tetrasodium hydrate (459836-30-7 free base)) is an orally available NMDA antagonist that is potent and selective. The IC50 value...
T13112	Tat-NR2B9c	500992-11-0	98%
T13112	Tat-NR2B9c (NA-1) is a postsynaptic density-95 (PSD-95) inhibitor with neuroprotective and antiepileptic effects.Tat-NR2B9c inhibits PSD-95d2, PSD-95d1, and PSD-...
T6259	Dizocilpine	77086-21-6	98%
T6259	MK-801 (Dizocilpine (MK-801)) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.
T6618	Orphenadrine Citrate	4682-36-4
T6618	Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.
TQ0289	LY450108	376594-67-1	100%
TQ0289	LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
T8459	DNQX disodium salt	1312992-24-7	100%
T8459	DNQX disodium salt is a water-soluble form of selective antagonist of non-NMDA receptor
T8435	YM90K	154164-30-4	100%
T8435	YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.
T7706	LY-404187	211311-95-4	100%
T7706	LY404187 is a positive allosteric modulator of AMPA receptors